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KMID : 0604520180440020151
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Journal of the Society of Cosmetic Scientists of Korea
2018 Volume.44 No. 2 p.151 ~ p.159
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Anti-oxidative Activities for the Flavonoids of the Syzygium aqueum Burm.f. Alston Branches from Jeju Island
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Yeum Hyun-Sook
Lee Nam-Ho
Hyun Ju-Mi
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Abstract
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In this study, we investigated the anti-oxidative activities and cell protective effects of the constituents isolated from S. aqueum branches. DPPH and ABTS+ radical scavenging activities were screened for the ethanol extract and solvent fractions, ethyl acetate (EtOAc) and butanol (BuOH) fractions showed potent activities. When HaCaT cells were treated with H2O2, the ethanol extract and EtOAc fractions (20 μ g/mL) protected the cells against oxidative damage. Two constituents were isolated from the EtOAc fraction of S. aqueum branches; pinocembrin (1), desmethoxymatteucinol (2). The chemical structures of the isolated compounds were elucidated based on the spectroscopic data including 1H and 13C NMR spectra, as well as comparison of the data to the literature values. Anti-oxidative activities and cell protective effects were studied for the isolated compounds. For the anti-oxidative activities, all of the compounds 1 and 2 showed DPPH and ABTS+ radical scavenging activities. Also, from the cell protective effect test, the compounds 1 and 2 protected the cell against oxidative stress by H2O2. Based on these results, S. aqueum branches extract could be potentially applicable as anti-oxidant ingredients in cosmetic industries.
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KEYWORD
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S. Aqueum, anti-oxidation, cell protective effect, isolation, flavonoid
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